Aggrenox as a Phosphodiesterase Inhibitor
Question #8
Aggrenox is a combo drug of ASA and dipyridamole that may be prescribed to cardiac patients. However I just read that dipyridamole is a phosphodiesterase inhibitor. Just to confirm, does this mean patients with pre-existing cardiac conditions who are on Aggrenox are contraindicated for nitroglycerin administration? What if their doctor has prescribed them both Aggrenox and nitro?
Answer:
This is a great observation and great question. Fortunately, we shouldn't have to worry about this going forward as Dr. Moran has advised us that Aggrenox is no longer available in Canada.
Medical Directive Category
Cardiac Ischemia
Published
23 January 2025
ALSPCS Version
5.3
Views
35
Please reference the MOST RECENT ALS PCS for updates and changes to these directives.